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Scientists Identify Gene That First Slows, Then Accelerates, ALS in Mice

From the lab of Tom Maniatis, PhD, Columbia's Zuckerman Institute

Representative confocal microscope image of the ventral horn of the spinal cord from an ALS mouse. Several microglial cells (green) infiltrate the spinal cord as ALS disease progresses. Single molecule FISH detected IRF7 (an interferon-inducible gene) RNA molecules (red) in microglia and other cells (Credit: Valeria Gerbino/Maniatis lab/Columbia’s Zuckerman Institute).

News from about

Disease March 27, 2020

Scientists Identify Gene That First Slows, Then Accelerates, ALS in Mice

Columbia study underscores complexities of deadly neurodegenerative disease; offers promising strategies to target disease’s underlying genetic mechanisms.

The Senses March 9, 2020

Curious Minds: How Do Flies See in Color?

New research from two young scientists shows how the brains of flies, like the brains of humans, create the mental illusion of color.

March 3, 2020

International Women's Day: Elizabeth Hillman's Magic Microscopes

This International Women's Day, meet Biomedical Engineer Elizabeth Hillman. She is inventing new kinds of microscopes that create 3D movies of life in action.

Decision Making February 26, 2020

How Does the Brain Put Decisions into Context?

Columbia research combines mathematics and neuroscience; highlights surprising power of one brain area to simultaneously integrate vast amounts of information.

Disease February 19, 2020

Curious Minds: Can You Inherit Stress on Your DNA?

Do the experiences of your father leave a mark on your genes? Can trauma be passed down from generation to generation?

Decision Making February 14, 2020

How the Brain Makes Decisions Without Language

A Q&A with Herbert Terrace, Vincent Ferrera and Greg Jensen.

The Senses February 12, 2020

Curious Minds: How Do We Taste Sour?

How do the tongue and the brain work together to tell us that certain things are sour?

Disease February 6, 2020

Toxic Protein, Linked to Alzheimer’s and Other Diseases, Exposed in New Detail

Columbia-led team harnesses two powerful technologies to identify promising targets for diagnosing and treating neurodegenerative diseases.

The Senses February 4, 2020

Columbia’s Zuckerman Institute Announces Three Artists-in-Residence

Year-long program embeds award-winning painter, jazz musician and author with scientists studying the mind, the brain and behavior.

The Senses January 29, 2020

Sex Pheromone Named for Jane Austen Character Alters Brain in Mouse Courtship

Columbia-led study in mice maps brain circuitry that enables a single pheromone to drive both innate and learned sexual behaviors

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