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Can Tangled-Up Neurons Lead to Depression-Like Behavior?

Tom Maniatis

From the lab of Tom Maniatis, PhD, Columbia's Zuckerman Institute

Confocal immunofluorescence image showing the spacing of serotonergic fibers in a mouse brain (Credit: Weisheng Chen/Tom Maniatis/Columbia's Zuckerman Institute).

News from about

The Senses August 9, 2017

How the Tongue Keeps Its Tastes Straight

Signals sent by tongue’s taste cells prevent the brain from confusing bitter and sweet tastes.

Decision Making July 27, 2017

Scientists Witness the Brain’s ‘Aha!’ Moment

Study lends insight into one of neuroscience’s greatest puzzles: how the brain transforms unconscious information into conscious thought.

Movement July 20, 2017

How Patterns of Brain Activity Direct Specific Body Movements

Study in mice answers long-standing scientific question about the brain’s ability to drive movement

Learning & Memory June 27, 2017

Learning, Memory and Movement: Revealing Connections Behind the Brain’s Talents

Whether it’s hitting a homerun or a tickling the ivories, neuroscientist Rui Costa, PhD, investigates how we learn skilled movement — and what happens in the brain when that ability is disrupted.

Tools & Technology June 16, 2017

Building the Tools to Revolutionize Brain Research

At the 2017 World Science Festival, scientists shared their insights into how technology is advancing what we can uncover about the brain — and how that knowledge stands to improve health and society

The Senses May 22, 2017

How the Brain Turns Down the Volume on Your Noisy Body

A Q&A with Nathaniel Sawtell, PhD

Nathaniel Sawtell, PhD
Disease April 27, 2017

Can Tangled-Up Neurons Lead to Depression-Like Behavior?

Twin papers lend clues into how the brain organizes itself, offering new avenues for studying psychiatric disorders.

Decision Making April 7, 2017

Curious Cells: How the Brain Makes Up Its Mind

A Q&A with Jacqueline Gottlieb, PhD

Movement February 23, 2017

Mastering New Movements

In his research, Rui Costa asks: How does the brain discover and refine new behaviors?

Evolution February 9, 2017

Pinpointing the Genes Behind Fine Motor Skills

Researchers have found a genetic signature located exclusively in the nerve cells that supply, or innervate, the muscles of an organism’s outermost extremities: the hands and feet.

red and gree fluorescent dye marks specific genes for digit-innervating motor neurons in the developing foot