Columbia University in the City of New York

Science

Disease

Disease

Brain Cell Loss Linked to Schizophrenia

From the lab of Joseph A. Gogos, MD, PhD, Columbia's Zuckerman Institute

Depleted cells in the CA2 brain region (blue) of a mouse, which cause deficits in social memory (Credit: Vivien Chevalyre/Gogos Lab /Columbia's Zuckerman Institute/Columbia University Medical Center).

The best medicine treats not the symptoms of an illness – but its underlying causes.

Yet even today, doctors do not know the exact causes of many brain diseases, which remain complicated and confusing. Battling diseases such as Alzheimer’s and Parkinson's will require fundamental leaps in understanding.

At Columbia’s Zuckerman Institute, our researchers study how healthy nervous systems work to better understand sickness. Which genes help nerves to function properly? What molecules keep the brain working from moment to moment, and what happens when they go awry? How do systems in the brain communicate to give rise to the everyday activities of our minds, from decision making to memory formation?

Advances in fundamental knowledge about the brain today will lay the foundation for future innovations in treating and curing disease. Our work can further the goals of clinical researchers who target diseases of the brain and disorders of the mind, ranging from Alzheimer’s and Parkinson’s to schizophrenia and autism.

Explore Disease

In the news

View All News >

Featured Videos

Long-term Memories Are Maintained by Prion-like Proteins

Writing a New Story Together: Confronting Mental Health Disparities with Community Partnerships

Can Children Save the Lives of Their Parents in the Throes of Stroke?

Neurons’ Faulty Wiring Leads to Serotonin Imbalance, Depression-Like Behavior in Mice

Hope in the Face of Fear: 
Using Neuroscience to Transform Treatments for Anxiety and OCD

Heading Off Damage: New Insights in Traumatic Brain Injury

|