Columbia University in the City of New York

Scientists Paint Multicolor Atlas of Worm Nerve Cells

A new technique developed by Columbia researchers helps tease out the dynamics of neural networks in the nervous system of microscopic worms.

In this coiled NeuroPAL worm, every neuron can be identified by its color. (Credit: Eviatar Yemini / Oliver Hobert / Department of Biological Sciences at Columbia)

Columbia scientists have engineered a coloring technique, known as NeuroPAL (a Neuronal Polychromatic Atlas of Landmarks), which makes it possible to identify every single neuron in Caenorhabditis elegans (C. elegans), a worm species commonly used in biological research. 

The research from the laboratory of Oliver Hobert, PhD, Professor at Columbia University Department of Biological Sciences and an affiliate member of the Zuckerman Institute, in collaboration with Liam Paninksi, PhD, Principal Investigator at Columbia's Zuckerman Institute, was published in the Jan. 7 issue of the journal Cell.

To learn more please visit Columbia News.

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