Yueqing Peng, PhD
Assistant Professor, Department of Pathology and Cell Biology (in Neurology)
Columbia University Irving Medical Center
Host(s): Carol Mason (Faculty)
Regulation and function of NREM sleep
Sleep is a universal biological phenomenon for most organisms. Understanding the regulation and function of sleep is a fundamental goal of neurobiology and important for the development of new treatments for insomnia and sleep-related brain diseases. Yet, brain circuits underlying this process remain poorly understood. Here, I will discuss some of our recent work to tackle how the brain regulates sleep and what function sleep plays in memory. In the first part, I will talk about a population of glutamatergic neurons in the ventrolateral medulla (VLM) that control the transitions from wakefulness to NREM sleep. In the second part, I will discuss the newly identified infraslow oscillation of neural activity in the dentate gyrus that occurs during NREM sleep and modulated by the 5-HT system.
Relevant Publications:
Serontonin modulates infraslow oscillation in the dentate gyrus during Non-REM sleep
This event will be in-person only, open to Columbia University Affiliates
Speaker Location: Jerome L. Greene Science Center, Kavli Auditorium, 9th Floor Lecture Hall
Tuesdays@10 is a signature Zuckerman Institute initiative that aims to expose researchers at all levels to high-quality science and stimulate scientific discourse. The speakers featured in this series represent various fields and techniques in neuroscience, and include invited guests of the Columbia Neuroscience Seminars, the Zuckerman Institute's Local Circuits Affiliates Program, and other special seminar series through a combined, collaborative effort of one or more of the following: Columbia's Zuckerman Institute, the Center for Precision Psychiatry, the Department of Neuroscience, the Doctoral Program in Neurobiology and Behavior and the Columbia Translational Neuroscience Initiative, and with support from the Kavli Institute for Brain Science.
More information and a full schedule can be found here.