Vikaas Sohal, MD, PhD
Professor, Department of Psychiatry and Behavioral Sciences
UCSF
Host(s): Attila Losonczy (Faculty) and Carl Shi (PhD Student)
The role of interneuron-generated synchrony in cognition and emotion
Oscillations are ubiquitous in neural systems and often associated with neuropsychiatric conditions. Still, the idea that they play important roles in brain function remains highly contentious. I will discuss recent work from our lab demonstrating two cases in which rhythmic synchrony between GABAergic interneurons plays important roles in brain function. First, I will discuss the role of prefrontal gamma synchrony in cognitive flexibility, and potential implications for treating cognitive deficits in schizophrenia. Second, I will discuss back-translation and circuit dissection of a synchrony-based biomarker for emotional states that we originally discovered in the human brain.
Relevant Publications:
Long-range inhibition synchronizes and updates prefrontal task activity
Venue Information:
Speaker Location: Jerome L. Greene Science Center, Kavli Auditorium, 9th Floor Lecture Hall
The Columbia Neuroscience Seminars have been organized to help build community and collaboration among researchers interested in this broad field across campus. The in-person activities, including the talks, provide meaningful interactions for the speakers, many of whom have traveled a long way to visit Columbia. However, if you are a Columbia researcher on another campus and are unable to attend the talk at the Jerome L. Greene Science Center, please email [email protected] at least 48 hours in advance to request an individual, one-time Zoom link (livestream only, no Q&A).
If you have a short- or long-term accommodation request (medical issue, travel, other concerns, etc.), or any other questions, please also reach out to [email protected].
Tuesdays@10 is a signature Zuckerman Institute initiative that aims to expose researchers at all levels to high-quality science and stimulate scientific discourse. The speakers featured in this series represent various fields and techniques in neuroscience, and include invited guests of the Columbia Neuroscience Seminars, the Zuckerman Institute's Local Circuits Affiliates Program, and other special seminar series through a combined, collaborative effort of one or more of the following: Columbia's Zuckerman Institute, the Center for Precision Psychiatry, the Department of Neuroscience, the Doctoral Program in Neurobiology and Behavior and the Columbia Translational Neuroscience Initiative, and with support from the Kavli Institute for Brain Science.
More information and a full schedule can be found here.