Columbia University in the City of New York

Our Leadership

Led by Rui Costa, DVM, PhD, and Nobel laureates Richard Axel, MD, and Eric Kandel, MD, we study critical aspects of the mind and brain, gaining insights that promise to benefit people and societies everywhere.

Rui M. Costa, DVM, PhD

Director and Chief Executive Officer

Rui Costa is director and chief executive officer of Columbia’s Mortimer B. Zuckerman Mind Brain Behavior Institute and a professor of neuroscience and neurology at Columbia's Vagelos College of Physicians and Surgeons. In his role Dr. Costa is responsible for the administrative, financial and scientific management of the Institute. Prior to being named director, he served as associate director and CEO of the Zuckerman Institute from 2017-2019. Dr. Costa has substantial experience in institutional leadership for neuroscience research. Prior to joining Columbia in 2016, he was Director of Research at the Champalimaud Centre for the Unknown in Lisbon, Portugal.

Richard Axel, MD


Richard Axel is a Nobel laureate; a University Professor; an investigator at the Howard Hughes Medical Institute and Columbia's Vagelos College of Physicians and Surgeons and a codirector of Columbia’s Mortimer B. Zuckerman Mind Brain Behavior Institute. Dr. Axel obtained an AB from Columbia College and an MD from Johns Hopkins Medical School. In earlier studies, Dr. Axel and his colleagues, Michael Wigler and Saul Silverstein, developed gene transfer techniques that permit the introduction of virtually any gene into any cell. These studies not only allowed for a novel approach to isolate genes but also provided a detailed analysis of how they worked. At the same time, these experiments allowed for the production of an increasingly large number of clinically important proteins. These studies also led to the isolation and functional analysis of a gene for the lymphocyte surface protein, CD4, the cellular receptor for the AIDS virus, HIV.

Eric Kandel, Nobel Prize winner and Co-Director of the Zuckerman Institute

Eric R. Kandel, MD


Eric R. Kandel is a Nobel laureate; University Professor and Sagol Professor of Brain Science; Codirector of Columbia's Zuckerman Institute; Founding Director of Columbia's Kavli Institute for Brain Science and a Senior Investigator at the Howard Hughes Medical Institute. A graduate of Harvard College and NYU School of Medicine, Dr. Kandel trained in neurobiology at the NIH and in psychiatry at Harvard Medical School. He joined the faculty of the College of Physicians and Surgeons at Columbia University in 1974 as the founding director of the Center for Neurobiology and Behavior. At Columbia Dr. Kandel organized the neuroscience curriculum. He is an editor of Principles of Neural Science, the standard textbook in the field, now in its fifth edition. In 2006, Dr. Kandel wrote a book on the brain for the general public entitled In Search of Memory: The Emergence of a New Science of Mind, which won both the L.A. Times and U.S. National Academy of Science Awards for best book in Science and Technology in 2008. A documentary film based on that book is also entitled In Search of Memory. In 2012 Dr. Kandel wrote The Age of Insight: The Quest to Understand the Unconscious in Art, Mind, and Brain, from Vienna 1900 to the Present, which won the Kreisky Award in Literature, Austria’s highest literary award. Dr. Kandel’s newest book, entitled Reductionism in Art and Brain Science: Bridging the Two Cultures, published by Columbia University Press, was released in Fall 2016.

To close the gap between our genetic and molecular understanding of the brain and what the social sciences, humanities, and professional disciplines tell us about behavior, we are creating a place for scholarship where a spirit of common inquiry yields extraordinary discoveries.
Lee C. Bollinger
President, Columbia University