Cagla Eroglu, PhD
Duke Health Distinguished Professor of Cell Biology
Duke University
Host(s): Stephanie Herrlinger (Postdoc)
How do Astrocytes Sculpt Synaptic Circuits?
How are synaptic networks formed during development and remodeled during learning and disease? This is the main question that drives our research. In particular, we investigate the roles of glial cells called astrocytes in the development, remodeling and function of synaptic circuits. In my talk, I will share findings from my lab on several distinct molecular mechanisms through which astrocytes control synapse formation and function and discuss how synaptogenic astrocyte signals are critical for proper development of the nervous system.
Related Publications:
Neuroligin-2 is ubiquitinated by Nedd4l to control developmental astrocyte morphogenesis
Tuesdays@10 is a signature Zuckerman Institute initiative that aims to expose researchers at all levels to high-quality science and stimulate scientific discourse. The speakers featured in this series represent various fields and techniques in neuroscience, and include invited guests of the Columbia Neuroscience Seminars, the Zuckerman Institute's Local Circuits Affiliates Program, and other special seminar series through a combined, collaborative effort of one or more of the following: Columbia's Zuckerman Institute, the Center for Precision Psychiatry, the Center for Theoretical Neuroscience, the Department of Neuroscience, the Doctoral Program in Neurobiology and Behavior and the Columbia Translational Neuroscience Initiative, and with support from the Kavli Institute for Brain Science.
More information and a full schedule can be found here.