This seminar will be held online. Register here. 

To make adaptive decisions we must cast ourselves into the future and consider the outcomes of our potential choices. This prospective consideration is informed by our memories. I will discuss our lab’s recent work investigating the neural circuits responsible for encoding, updating, and retrieving reward memories for use in the considerations underlying decision making. We have taken a multifaceted approach to these investigations, combining recording, circuit dissection, and behavioral tools. Our results are indicating that the orbitofrontal cortex and basolateral amygdala work in a circuit to regulate the encoding and retrieval of reward memories to ensure adaptive reward pursuit. The cognitive symptoms underlying addiction can result from a failure to appropriately learn about and/or anticipate potential future events, making these basic science data relevant to the understanding and potential treatment of addiction to drugs or alcohol.

Those who wish to meet the speaker during their visit should contact Carter Daniels or Basak Akdogan.

The Columbia Neuroscience Seminar series is a collaborative effort of Columbia's Zuckerman Institute, the Department of Neuroscience, the Doctoral Program in Neurobiology and Behavior and the Columbia Translational Neuroscience Initiative, and with support from the Kavli Institute for Brain Science.